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BIOCHEMICAL ASSAYS

BioMedha offers a wide range of high-quality expertise in biochemical assays and supports characterisation of compounds to meet the specific needs of our client projects from hit identification to candidate selection.  Our biochemical assay services feature:

  • Assay development and screening
  • In vitro characterization of compounds for potency, selectivity and mechanism of action and assay interference.
  • Enzyme activity (e.g. Kinases, Deubiquitinases, Lipase, HDACs, Amino-peptidases)
  • Ligand-binding assays (e.g., FP-, FRET-based assays)
  • Post-translation modifications, such as phosphorylation, ubiquitination, acetylation, methylation, sumoylation, hydroxylation and glycosylation
  • Protein-protein interactions
  • Redox activity

We receive compounds from clients, third-parties on behalf of clients and compound library vendors regularly to profile compounds against screening cascades.