cell imaging

Cell imaging allows visual and quantitative measurements to understand cellular processes, behaviour, target expression, function and how test compounds effects at cellular levels. We support client projects using this capability from target validation, phenotypic assays, hypothesis testing and compound profiling.

We offer both standard and bespoke services to meet client project requirements supporting early stage drug discovery pipeline. 

Our Cell Imaging expertise includes:

  • Cell painting: staining for multicolour phenotypic profiling: e.g., Staining of nuclei, cytoplasm, plasma membrane, mitochondria, endoplasmic reticulum, Golgi, cell marker studies, and etc
  • Cell health assays: e.g., cell proliferation, cytotoxicity, apoptosis, Cell migration/ Wound healing, angiogenesis, neurite outgrowth and cell differentiation
  • Live cell imaging: studying dynamic cellular processes, behaviour, and function
  • Immunofluorescence Imaging
  • Cell signalling and reporter assays
  • GPCR assays: GPCR internalisation and Transfluor® assay to screen GPCR ligands
  • Translocation/ Internalisation studies: autophagy, endosome, Lysosome, phagosomes, mitochondrial assays, endocytosis, and pits & vesicles formation
  • Co-culture assays
  • Toxicology studies: DNA damage, Neurotoxicity, cardiotoxicity, hepatotoxicity, and hematopoietic toxicity assessment
  • Microscopy types: Bright-field, Fluorescence and Digital confocal microscopy
  • Cell types: immortalised cell lines, recombinant cell lines, immune cells, primary cells, and iPSC derived cells such as Neurons, Microglia, Astrocyte, and Cardiomyocytes

Contact us to learn more about how we can help support your projects.