CYTOTOXICITY & Cell health assays

BioMedha has expertise in the development of cell health assays tailored to client needs and drug discovery project goals using normal or disease-relevant, immortalised or iPSC derived cell models. We offer complete support from assay development to compound profiling for identifying drug effects on cell health, ranking compounds for potency and investigating the cellular changes in disease areas such as cancer, autoimmune disease and neurodegeneration. Screening platforms include:

  • Cell proliferation, Cytotoxicity and Apoptosis assays
  • Colony Formation Assays
  • Cell adhesion and Cell Invasion assays
  • Phagocytosis, Mitophagy and Autophagy
  • Oxidative stress and Hypoxia
  • Cellular energy metabolism assays (Glucose uptake, NAD co-factor)
  • Metabolite assays (Glucose and Glutamine consumptions; Lactate and Glutamine secretion)
  • Phospholidosis
  • Cyp, Pgp and UGT activity
  • hERG activity: FP based assay