Understanding and managing compound toxicity at the earliest possible stage is important to improve safety and efficacy of therapeutic molecules in drug development. In vitro toxicology assays developed at BioMedha are cost effective, high-throughput, and non-GLP to facilitate efficient safety profiling at the early stages of the drug discovery pipeline.

Our in-house experts have developed standardized In vitro toxicology assays so that you can receive timely data to advance your drug discovery projects. We support client projects by identifying compounds that induce toxicity in order to de-risk the early-stage drug discovery pipeline. We offer both standard and bespoke services to meet client project requirements.

Our discovery toxicology assays include:

  • Mitochondrial toxicity studies
  • hERG Binding Assay (FP based)
  • Cytotoxicity
  • DNA Damage (Phospho-H2AX-Ser139)
  • Hepatotoxicity: CYP450, Pgp, UGT activity, Phospholipidosis, and Steatosis
  • ATP Inhibition, ROS, Oxidative Stress
  • Calcium Flux
  • Neurotoxicity
  • Energy Metabolism assays

Get in contact with our team to learn more about how we can support your projects.