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Mitochondrial TOXICITY ASSESSMENT

BioMedha offers wide range of mitochondrial toxicity assessment studies supporting client projects to identify compounds that induce toxicity and De-risking early stage drug discovery pipeline. We offer both standard and bespoke services based on client’s project requirements. Assay formats include:

  • Both functional & mechanistic studies
  • Mitochondrial membrane potential
  • ATP synthesis (+/ - glucose)
  • Oxygen consumption (OCR)
  • Glycolytic flux/ extra-cellular acidification (ECAR)
  • Electron transport chain activity/ OXPHOS enzyme activity
  • Antioxidant activity and Metabolic enzyme activity