Mitochondrial TOXICITY ASSESSMENT
BioMedha offers wide range of mitochondrial toxicity assessment studies supporting client projects to identify compounds that induce toxicity and De-risking early stage drug discovery pipeline. We offer both standard and bespoke services based on client’s project requirements. Assay formats include:
- Both functional & mechanistic studies
- Mitochondrial membrane potential
- ATP synthesis (+/ - glucose)
- Oxygen consumption (OCR)
- Glycolytic flux/ extra-cellular acidification (ECAR)
- Electron transport chain activity/ OXPHOS enzyme activity
- Antioxidant activity and Metabolic enzyme activity