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Mitochondrial TOXICITY

BioMedha offers wide range of mitochondrial studies to support client projects such as mitochondrial toxicity assessment, neurological disorders (Parkinson’s and Alzheimer’s) and cancer. We offer bespoke assay development and compound profiling expertise to support client’s screening cascade requirements. Assay formats include:

  • Both functional & mechanistic studies
  • Mitochondrial membrane potential
  • Oxygen consumption (OCR)
  • Glycolytic flux/ extra-cellular acidification (ECAR)
  • Electron transport chain activity
  • ATP production (+/ - glucose)
  • Mitochondrial biogenesis
  • Antioxidant activity
  • Metabolic enzyme activity