Mitochondrial TOXICITY

BioMedha offers a wide range of assays for assessing mitochondrial toxicity and dysfunction. We support client projects by identifying compounds that induce toxicity in order to de-risk the early-stage drug discovery pipeline. We offer both standard and bespoke services to meet client project requirements.

Assay formats include:

  • Both functional & mechanistic studies
  • Mitochondrial membrane potential
  • ATP synthesis (+/ - glucose)
  • Oxygen consumption (OCR)
  • Glycolytic flux/ extra-cellular acidification (ECAR)
  • Electron transport chain activity/ OXPHOS enzyme activity
  • Antioxidant activity and Metabolic enzyme activity

Contact us to learn more about how we can help support your projects.