Mitochondrial TOXICITY
BioMedha offers a wide range of assays for assessing mitochondrial toxicity and dysfunction. We support client projects by identifying compounds that induce toxicity in order to de-risk the early-stage drug discovery pipeline. We offer both standard and bespoke services to meet client project requirements.
Assay formats include:
- Both functional & mechanistic studies
- Mitochondrial membrane potential
- ATP synthesis (+/ - glucose)
- Oxygen consumption (OCR)
- Glycolytic flux/ extra-cellular acidification (ECAR)
- Electron transport chain activity/ OXPHOS enzyme activity
- Antioxidant activity and Metabolic enzyme activity
Contact us to learn more about how we can help support your projects.