EXPRESSION STUDIES
BioMedha offers a range of expression study assay formats to help provide a better understanding of disease biology, associated pathways, and compound efficacy.
Target expression pattern provides valuable insight in target validation, understanding biology, and molecular basis for compound effect, therapeutic efficacy, and to rule out any associated drug toxicity.
Our expression studies include:
- Gene expression by qPCR
- Total protein levels by Western blotting
- Secretion levels by ELISA / AlphaLisa / HTRF/ Luminex
- Surface expression by flowcytometry
- Expression by immunofluorescence imaging
- Transcription factors activation by hybridisation
- Measuring a compound's effect on a target
- Transfections and transductions
- Gene knockdown studies (siRNA)
- Target validation (In vitro)
- Biomarker levels
- Residual DNA analysis
- Custom assay development and screening
- Sample type: cells, blood, and tissue (e.g. xenograft)
- Species: human, rat, mouse, and canine