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Microglia assays
We utilise iPSC microglia assays as In vitro models for microglia mediated neuroinflammation. iPSC Microglia were characterised for TMEM119 and CD11b phenotypic markers (by cell imaging and flowcyte) and validated by cytokine release, phagocytosis, chemotaxis, and cell morphology.
Characterisation
Functional response - Validation
Here we demonstrate successful culture of iPSC derived microglia, characterised by expression of microglia phenotypic markers, and validated by functional response pattern demonstrating relevance. Validated microglia assays at BioMedha enabled us supporting client’s programmes, measuring compound effect (to assess therapeutic efficacy) on Microglia function and gene expression.